
产品货号:
Z10985
中文名称:
AP2M1抗体
英文名称:
Anti-AP2M1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-AP2M1 Antibody |
指标别名 | Adaptin mu2;AP 2 complex subunit mu;AP 2 mu chain;AP2M1;AP50;CLAPM1;HA2 50kDa subunit;KIAA0109;mu2 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | AP2M1 |
抗体来源 | Chicken |
抗体类型 | IgY |
免疫原 | AP2M1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human AP2M1.The immunogen is located within amino acids 360 - 410 of AP2M1. |
计算分子量 | 50kDa |
成分 | AP2M1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | AP2M1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The heterotetrameric coat assembly protein complex,also known as the adaptor-related protein complex 2 (AP-2),belongs to the adaptor complexes medium subunits family.The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase,which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes.AP2M1 has also been shown to associate with the HIV-1 protein Nef,suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC.AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein.At least two isoforms of AP2M1 are known to exist. |
Uniprot ID | Q96CW1 |
基因名全称 | Adaptor-related protein complex 2,mu 1 subunit |
蛋白名全称 | Adaptor-related protein complex 2,mu 1 subunit |
推荐稀释比 | AP2M1 antibody can be used for detection of AP2M1 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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